WATCH-TAVR: WATCHMAN™ for patients with atrial fibrillation undergoing transcatheter aortic valve replacement

General Information Age Group Adults Status Recruiting Protocol Number N/A Background Information The purpose of this study is to look at the safety and effectiveness of the WATCHMAN™ device procedure when it is done in combination (at the same time) with the TAVR procedure. This combined approach will be compared to the TAVR procedure along with medical treatment only for an extended period of time. Offered At Inova Fairfax Hospital 3300 Gallows Road Falls Church, VA 22042 Principal Investigator Wayne Batchelor, MD Eric Sarin, MD Eligibility Information Diagnosed as having atrial fibrillation (AF or AFib) and aortic stenosis (AS) requiring a Transcatheter Aortic Valve Replacement (TAVR) Documented paroxysmal, persistent, or permanent atrial fibrillation Patient is eligible to undergo WATCHMAN implantation procedure Patient is eligible for short term warfarin therapy Ineligibility Information Patient had stroke or TIA within 6 months prior to enrollment Contradiction for short term anticoagulation Moderate or severe mitral stenosis Patient had symptomatic carotid disease Prior occlusion of LAA Patient has an implanted mechanical mitral valve Patient requires long-term warfarin therapy due to: prior arterial embolism, pulmonary embolism within previous 6 months. Contact Information Contact Name Micaela Davidow Contact Phone 703-776-4713 Contact Information Contact Name Ana Villagomez Contact Phone 703-776-6007