Carcinoma of Unknown Primary See All Overview See All Understanding Your Diagnosis See All Deciding on Treatment See All Managing Side Effects See All Cancer FAQs See All Cancer of Unknown Primary: Introduction in Overview Cancer of unknown primary (CUP) is cancer that starts in an unknown area and has already spread by the time it's diagnosed. ...more Cancer of Unknown Primary: Risk Factors in Overview Because healthcare providers don't know the why, how, or where of cancer of unknown primary origin (CUP), it's hard to identify risk factors for it. ...more Cancer of Unknown Primary: Newly Diagnosed in Understanding Your Diagnosis Being told you have cancer of unknown primary (CUP) can be scary, and you may have many questions. But you have people on your healthcare team to help. ...more Cancer of Unknown Primary: Diagnosis in Understanding Your Diagnosis If your healthcare provider thinks you might have cancer of unknown primary (CUP), you will need certain exams and tests to be sure. These tests will be used to try to find the place the cancer started. ...more Cancer of Unknown Primary: Treatment Choices in Deciding on Treatment You may get just 1 type of treatment or a combination of treatments. Treatment may include chemotherapy, radiation therapy, hormone therapy, or surgery. ...more Cancer of Unknown Primary: Chemotherapy in Deciding on Treatment Chemotherapy can shrink tumors. It can also help ease symptoms the cancer is causing. It may even make some tumors go away. ...more Managing Cancer-Related Fatigue in Managing Side Effects, Other Treatment Side Effects Fatigue can come and go or stay constant for a while. Fatigue from chemotherapy tends to happen a few days after the treatment, peaks, and then gets better before the next treatment. Fatigue from radiation may not happen right away. ...more Anemia and Chemotherapy in Chemotherapy Side Effects Chemotherapy can damage your body’s ability to make red blood cells, so body tissues don't get enough oxygen. This is a condition called anemia. People who have anemia may feel very weak or tired, dizzy, faint, or short of breath, or may feel that their hearts are beating very fast. ...more Infection and Chemotherapy in Chemotherapy Side Effects To reduce your risk for infection, avoid people who are sick with contagious illnesses, including colds, the flu, measles, or chickenpox. ...more Cancer of Unknown Primary: Radiation Therapy in Deciding on Treatment, Other Treatment Side Effects Radiation may be used to treat the symptoms of cancer of unknown primary (CUP). Sometimes radiation may also be used to cure the cancer if it hasn't spread too far. ...more Cancer of Unknown Primary: Surgery in Deciding on Treatment, Other Treatment Side Effects During surgery, your healthcare provider removes a tumor or tumors from your body. Most of the time, they try to take out all the cancer and some of the normal tissue around it. ...more Carcinoma of Unknown Primary- Overview in Cancer FAQs In carcinoma of unknown primary (CUP), doctors can’t tell where the cancer started. CUP has already spread by the time it’s diagnosed. Learn more about symptoms, diagnosis, and treatments. ...more
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